Acute Kidney Failure: When Multiple Myeloma Doesn´t Give Additional Clues

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Multiple myeloma--presenting as acute kidney injury.

BACKGROUND Multiple myeloma (MM) is a commonly encountered hematological malignancy with significant renal involvement and often presents as renal failure. The aim of the present study is to analyze clinical spectrum of acute renal failure (ARF) in patients with MM. MATERIAL AND METHODS We analyzed 26 (males 24; females 2) patients of multiple myeloma who were referred for evaluation of ARF b...

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Multiple Myeloma Presenting as Acute Liver Failure

Liver failure is rarely caused by multiple myeloma (MM). We present an unusual case of MM initially presenting as acute liver injury. A 79-year-old man with new-onset fatigue, decreased appetite, and no history of liver disease was found to have evidence of hepatic decompensation. Liver biopsy demonstrated diffuse plasma cell infiltration, and MM was confirmed with bone marrow biopsy. Chemother...

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Multiple myeloma presented as acute renal failure

Multiple myeloma (MM) is a plasma cell dyscrasia and it most often occurs in old age adults. The mean age of the patients at diagnosis is 66 years old and only few percent of patients are younger than 40 years old (1,2). At the time of diagnosis, about 3% of MM patients have no M-protein in their serum or urine, based on immunofixation method (1-3). Approximately 50% of MM patients have at leas...

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Multiple myeloma presenting as acute renal failure.

CASE PRESENTATION A 68-year-old African American woman presented to the emergency department after routine blood work with her primary care physician revealed abnormal renal function studies. Six months prior to admission, she began to have nonspecifi c pain in her back, knees, and feet. Degenerative osteoarthritis was diagnosed, and she was treated with conservative measures including physical...

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Multiple Myeloma: Clusters, Clues, and Dioxins1

Multiple myeboma (MM) is a B-cell neoplasm of unknown etiology. We searched for etiological clues by examining the literature on geographic clusters of MM. We searched the MEDLINE database from 1966 to 1996 for spatial occurrences of MM that were significantly greater than expected (spatial “clusters”). Eight clusters with verified diagnoses of MM were identified. All of the eight clusters occu...

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ژورنال

عنوان ژورنال: Cureus

سال: 2020

ISSN: 2168-8184

DOI: 10.7759/cureus.7664